Transport of Gases - Carbon dioxide
Description:
Transport as Carbamino-haemoglobin
CO2 is carried as carbamino-haemoglobin.
When pCO2 is high and pO2 is low in tissues more binding of carbon dioxide occurs.
When pCO2 is low and pO2 is high as in alveoli, dissociation of CO2 from carbamino-haemoglobin takes place. CO2 bound to haemoglobin from the tissues is delivered at the alveoli.
Transport as Bicarbonate ions
Carbonic anhydrase enzyme is present in large quantities in the RBCs. The enzyme is also present in minute quantities in plasma.
Carbonic anhydrase can perform the following reaction −
At tissues the pCO2 is high due to catabolism so CO2 diffuses into blood and forms HCO-3 and H+
At alveoli, pCO2 is low so the reaction proceeds in the opposite direction. This leads to the formation of CO2 and H2O. So CO2 is transported in the form of bicarbonate and released out.
Every 100 ml of deoxygenated blood delivers about 4 ml of CO2 to the alveoli.