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Virus - AIDS


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Published on:  on 5th Dec, 2017

Description:

Virus related to Acquired Immune Deficiency Syndrome or AIDS which is caused by Human Immunodeficiency Virus or HIV.

Structure of the virus

  • The virus particle is covered by two lipid layers derived from the host cell.
  • Two types of glycoproteins are also associated with these lipid layers −

    • gp 41: Lie within lipid membrane.
    • gp 120: extends beyond lipid layers and forms a second layer.

  • The double layered envelope covers a double layered protein core.
  • Contains RNA as the genetic material.
  • The RNA codes for an enzyme reverse transcriptase.

AIDS Virus

Harmful effects of HIV

  • The virus attacks T 4 cells of host. These T 4 cells plays a major role in the immune system of the body.
  • It also affects the brain and spinal chord.
  • HIV can cause 3 types of cancer in infected persons −

    • Kaposi\'s sarcoma which is a type of skin tumor that spread to internal organs and cause internal bleeding and death.
    • Cancerous growth of skin and mucous membranes.
    • Tumors in B-lymphocytes.

Mechanism of action

  • Takes three to ten years of incubation during which no symptoms of AIDS are produced.
  • At the end of incubation period, the infected people develop AIDS related complex (ARC).
  • Causes the depletion of T-helper cells and continuously swollen lymph glands.
  • ARC is followed by the disease AIDS.

Mode of transmission

  • Sexual contact.
  • Contaminated blood and blood products.
  • Sharing of drug needs contaminated with the virus.
  • From infect mother to child during or shortly after birth.
  • Cannot be transmitted by casual contacts like shaking hands, hugging or food and water.


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